Daniela de Paulis is a former contemporary dancer and a media artist exhibiting internationally. She is also a licensed radio operator. Her artistic practice is informed by Space in its widest meaning. Since 2009 she has been implementing radio technologies and philosophies in her art projects. She is currently Artist in Residence at the SETI Institute and Artist in Residence at the Green Bank Observatory in West Virginia, with the support of the Baruch Blumberg Fellowship in Astrobiology.

She is collaborating with some prominent research institutes, including the European Space Agency, INAF (Italian Research Institute for Radio Astronomy), the Donders Centre for Neuroimaging and the University of Cambridge. For her projects, she is using state of the art radio telescopes, such as the Square Kilometre Array and the Mullard Radio Astronomy Observatory in the UK, the Medicina Radio Telescope and the Sardinia Radio Telescope in Italy. Previously, she has been collaborating with radio operators based at historical antennas, such as the Bochum Radio Observatory (DE) and the Dwingeloo radio telescope (NL). From 2009 she has developed the Visual Moonbounce technology, in collaboration with international radio operators, and a series of innovative projects combining radio technologies with live performance art and neuroscience. From 2010 to 2019 she has been collaborating with Astronomers Without Borders as the founder and director of the Arts programme. She has been collaborating with several other organizations, including the Human Space Program, lead by space philosopher Frank White, the Space and Society Working Group lead by philosopher James Schwartz.

She is a member of the IAA SETI (Search for Extraterrestrial Intelligence) Permanent Committee and  a regular host for the Wow! Signal Podcast, a platform dedicated to conversations on SETI, science, technology and the humanities. In addition to her artistic practice, she has published her work with the Leonardo MIT Journal, Routledge, Springer, Cambridge University Press and RIXC.