Daniela de Paulis is a former contemporary dancer and a media artist exhibiting internationally. She is also a licensed radio operator. Her artistic practice is informed by Space in its widest meaning. Since 2009 she has been implementing radio technologies and philosophies in her art projects. She is currently Artist in Residence at the SETI Institute (California) and Artist in Residence at the Green Bank Observatory (West Virginia), with the support of the Baruch Blumberg Fellowship in Astrobiology. She is collaborating with some prominent research institutes, including the European Space Agency, INAF (Italian Research Institute for Radio Astronomy), the Donders Centre for Neuroimaging and the University of Cambridge. For her projects, she is using state of the art radio telescopes, such as the Green Bank Telescope (West Virginia), the Allen Telescope Array (California), the Mullard Radio Astronomy Observatory (UK), the Medicina Radio Telescope and the Sardinia Radio Telescope (Italy).

Previously, she has been collaborating with radio operators based at historical antennas, such as the Bochum Radio Observatory (DE). In 2009 she has developed the Visual Moonbounce technology, in collaboration with international radio operators, and for the past fourteen years she has been working on a series of innovative projects combining radio technologies with live performance art and neuroscience. From 2010 to 2019 she has collaborated with Astronomers Without Borders as the founder and director of the Arts programme. She has been collaborating with several other organizations, including the Human Space Program, led by space philosopher Frank White, the Space and Society Working Group lead by philosopher Jayme Schwartz. She is a member of the IAA SETI (Search for Extraterrestrial Intelligence) Permanent Committee and a member of the UK SETI Hub. She is part of the committee organizer for the Electronic Visualisation in the Arts conference in London and part of the editorial board for the Springer Space and Society series.

In addition to her artistic practice, she has published academic papers with the Leonardo MIT Journal, Routledge, Springer, Cambridge University Press, Oxford University Press, Inderscience and RIXC, among others. She is the recipient of the Art of Neuroscience Prize 2022 with the project Mare Incognito, also shortlisted for other international festivals and featured on Scientific American. Her project A Sign in Space has been selected for the Billingham Cutting Edge Lecture at the International Astronautical Congress in 2022, and has been featured by international media outlets, including The New York Times, CNN, CBC, ABC Australia, Wired, Scientific American, as well as radio and television programmes. She is the winner of the Europlanet Prize for Public Engagement 2023.